Methadone Serve to Treat Opiate Cravings

There are problems with traditional medicine, starting with the simple observation that relapse rates have always been high. Increased relapse rates have implications for addiction that go beyond treatment options, as I will describe later. Another problem with traditional methods is that they require a great deal of motivation from patients–motivation that must be earned repeatedly throughout patients’ lives. Finally, a degree of detoxification is usually required prior to traditional treatment, requiring expensive treatment facilities that can be remote from the treatment site. The detox and withdrawal spectrum is the mainstay of treatment. Coming out is a unique experience, difficult to compare to other dysphoric experiences. Physical symptoms include headache, fatigue, nausea and vomiting, abdominal pain, nausea, and leg muscle weakness leading to involuntary movement. The withdrawer is usually highly depressed and anxious. The addict craves it, even though he can’t get drugs. These descriptions of symptoms do not do justice to the suffering experienced by the dependent opiate user. I also suspect that psychoanalysis is so affected by the use of ‘kindling’ that the symptoms get worse with each use, until eventually there is no such thing as a ‘simple cure’- the addict relates the dependence to it as badly as it did up to that point, regardless of the tolerance level at the withdrawal point. The sense of solidarity among addicts affected by their violent, unmedicated withdrawal is similar to that of disaster survivors. During withdrawal, however, the addict is overcome by intense loneliness.

Treatment alternatives have existed for many years that do not involve behavioral change and rely heavily on medications. Opiate maintenance with methadone and opiate blockade with naltrexone are two treatment options that are not associated with 12-step or cognitive therapy that can be used alone or in conjunction with traditional medicine. Methadone tablets in pakistan and naltrexone therapy overlap in many ways, but they also have some similarities. Methadone maintenance deliberately creates ‘hypertolerance’ to opiates, with daily administration of very high doses of opiates (usually methadone). This high tolerance precludes recreational opiate use, and higher daily doses of methadone serve to treat opiate cravings. Patients in methadone programs often feel trapped, so getting them off high doses of methadone is very difficult, and if they violate hospital policies (or have problems paying for the high cost of treatment) results in a dose reduction. People who regularly use methadone often report feeling ‘high’ all the time, regardless of tolerance. And while high doses of methadone will temporarily satisfy the craving, eventually tolerance will take over and the craving will return. There are other problems with methadone; some users report that methadone leads to a lack of motivation to better themselves through education or work. For decades, methadone tablet maintenance was associated with run-down suburbs where addicts could line up each morning to have their daily ‘fix’. Recent attempts have been made to ‘mainstream’ methadone care, with organ management, and sometimes moving to less disadvantaged communities. However, there were no changes to methadone monitoring protocols.

Naltrexone has already been partially discussed. The use of naltrexone is limited by the difficulty of achieving two weeks of sobriety before treatment; it takes that long for opiate users to recover to a level that blocks naltrexone use. Another problem is that the addict can ‘choose to do it’ by simply taking naltrexone for a couple of days. The use of naltrexone will make the patient more dependent on opiates, which can increase the likelihood of a fatal overdose. In addition to pills, naltrexone is sold as a monthly weight loss supplement, which helps minimize the problem of ‘choosing what to do’. The primary, interesting symptom of this drug is addiction rather than opiate dependence. Naltrexone has been shown to reduce alcohol cravings. A related form of naltrexone treatment is called ‘rapid opiate detoxification’, in which the addict is sedated and given withdrawal doses of naloxone intravenously. The addict is awakened 8 hours later with naltrexone that slowly releases the drug. This technique has gained popularity since reports of patients dying during anesthesia, or by suicide some time later.

Methadone maintenance mostly requires addicts to add morning medication intake to their daily schedules, which sometimes acts as a barrier to career development. Methadone tablet price in pakistan is Pkr 2500/- of 10 tablets and full packet is 25000/- in Pak Rupees with home delivery & free shipping within 2 to 3 days from TCS Courier, it contains 100 tablets full packet, it has to be taken 1 tablet in a week and it has no side effects. It is 100% original and imported by Iran.

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